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Substrate Induced Population Shifts and Stochastic Gating in the PBCV-1 mRNA Capping Enzyme
[Image: see text] The 317 residue PBCV-1 mRNA capping enzyme catalyzes the second enzymatic reaction in the formation of an N-7-methyl-GMP cap on the 5′-end of the nascent mRNA. It is composed of two globular domains bound by a short flexible peptide linker, which have been shown to undergo opening...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837470/ https://ncbi.nlm.nih.gov/pubmed/19301911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja808064g |
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