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Quantitative Comparison of Catalytic Mechanisms and Overall Reactions in Convergently Evolved Enzymes: Implications for Classification of Enzyme Function

Functionally analogous enzymes are those that catalyze similar reactions on similar substrates but do not share common ancestry, providing a window on the different structural strategies nature has used to evolve required catalysts. Identification and use of this information to improve reaction clas...

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Détails bibliographiques
Auteurs principaux: Almonacid, Daniel E., Yera, Emmanuel R., Mitchell, John B. O., Babbitt, Patricia C.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837397/
https://ncbi.nlm.nih.gov/pubmed/20300652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000700
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