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Use of a prolactin-Cre/ROSA-YFP transgenic mouse provides no evidence for lactotroph transdifferentiation after weaning, or increase in lactotroph/somatotroph proportion in lactation

In rats, a shift from somatotroph dominance to lactotroph dominance during pregnancy and lactation is well reported. Somatotroph to lactotroph transdifferentiation and increased lactotroph mitotic activity are believed to account for this and associated pituitary hypertrophy. A combination of cell d...

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Hlavní autoři: Castrique, Emma, Fernandez-Fuente, Marta, Le Tissier, Paul, Herman, Andy, Levy, Andy
Médium: Artigo
Jazyk:Inglês
Vydáno: BioScientifica 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837375/
https://ncbi.nlm.nih.gov/pubmed/20139144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1677/JOE-09-0414
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