Glutathione Pathway Genetic Polymorphisms and Lung Cancer Survival After Platinum-Based Chemotherapy

BACKGROUND: Lung cancer is commonly treated with platinum compounds. The “glutathione pathway” participates in the metabolism of platinum compounds. We set out to test the hypotheses that single nucleotide polymorphisms (SNPs) or copy number variation for genes within the glutathione pathway might i...

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Main Authors: Moyer, Ann M., Sun, Zhifu, Batzler, Anthony J., Li, Liang, Schaid, Daniel J., Yang, Ping, Weinshilboum, Richard M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837367/
https://ncbi.nlm.nih.gov/pubmed/20200426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0871
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