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Hydrolysis of 3-acetoxymethyl cephalosporins by lysed whole blood.

Cephalosporins having a 3-acetoxymethyl group are hydrolyzed to the corresponding desacetyl derivative by lysed whole blood but not by plasma or serum. When bioassays for this important class of cephalosporins must be run in whole blood or on tissues containing whole blood, steps should be taken to...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Wright, W E, Frogge, J A
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1980
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7352755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.1.99
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