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Hydrolysis of 3-acetoxymethyl cephalosporins by lysed whole blood.

Cephalosporins having a 3-acetoxymethyl group are hydrolyzed to the corresponding desacetyl derivative by lysed whole blood but not by plasma or serum. When bioassays for this important class of cephalosporins must be run in whole blood or on tissues containing whole blood, steps should be taken to...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Wright, W E, Frogge, J A
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1980
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283735/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7352755/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.1.99
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