Placenta growth factor in sickle cell disease: association with hemolysis and inflammation

Placenta growth factor (PlGF) is released by immature erythrocytes and is elevated in sickle cell disease (SCD). Previous data generated in vitro suggest that PlGF may play a role in the pathophysiology of SCD-associated pulmonary hypertension (PHT) by inducing the release of the vasoconstrictor, en...

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Autori principali: Brittain, Julia E., Hulkower, Ben, Jones, Susan K., Strayhorn, Dell, De Castro, Laura, Telen, Marilyn J., Orringer, Eugene P., Hinderliter, Alan, Ataga, Kenneth I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2010
Soggetti:
Red Cells, Iron, and Erythropoiesis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837320/
https://ncbi.nlm.nih.gov/pubmed/20040765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-04-217950
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