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Modified polyriboinosinic-polyribocytidylic acid complex: induction of serum interferon, fever, and hypotension in rabbits.

The purposes of this study were to determine whether the febrile and hypotensive reactions to the administration of polyriboinosinic-polyribocytidylic acid [poly (I)-poly (C)] complexed with poly-L-lysine and carboxymethylcellulose (poly ICLC) (9S) encountered in humans could be duplicated in rabbit...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Gatmaitan, B G, Legaspi, R C, Levy, H B, Lerner, A M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7352750/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.1.49
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