Identification of Peptide Ligands for Targeting to the Blood-Brain Barrier

PURPOSE: Transport of drugs to the brain is limited by the blood-brain barrier. New, specific brain endothelium ligands can facilitate brain-specific delivery of drugs. METHODS: We used phage display in an in situ brain perfusion model to screen for new brain endothelium peptide ligands. RESULTS: Tw...

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Detalhes bibliográficos
Main Authors: van Rooy, Inge, Cakir-Tascioglu, Serpil, Couraud, Pierre-Olivier, Romero, Ignacio A., Weksler, Babette, Storm, Gert, Hennink, Wim E., Schiffelers, Raymond M., Mastrobattista, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837178/
https://ncbi.nlm.nih.gov/pubmed/20162339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0053-6
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