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Cbfa1/Runx2-deficiency delays bone wound healing and locally delivered Cbfa1/Runx2 promotes bone repair in animal models

Core binding factor 1 (Cbfa1)/runt-related transcription factor 2 (Runx2) has been identified as a ‘‘master gene’’ in osteoblastic differentiation. In this two-part study, part I of the study was undertaken to test the hypothesis that bone regeneration is compromised in Cbfa1+/− mice. Compared with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tu, Qisheng, Zhang, Jin, James, Laji, Dickson, Julia, Tang, Jean, Yang, Pishan, Chen, Jake
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837142/
https://ncbi.nlm.nih.gov/pubmed/17537128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1524-475X.2007.00243.x
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