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Retroviral intasome assembly and inhibition of DNA strand transfer
Integrase is an essential retroviral enzyme that binds both termini of linear viral DNA and inserts them into a host cell chromosome. The structure of full-length retroviral integrase, either separately or in complex with DNA, has been lacking. Furthermore, although clinically useful inhibitors of H...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837123/ https://ncbi.nlm.nih.gov/pubmed/20118915 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08784 |
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