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Mitochondrial Dysfunction Confers Resistance to Multiple Drugs in Caenorhabditis elegans

In a previous genetic screen for Caenorhabditis elegans mutants that survive in the presence of an antimitotic drug, hemiasterlin, we identified eight strong mutants. Two of these were found to be resistant to multiple toxins, and in one of these we identified a missense mutation in phb-2, which enc...

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書誌詳細
主要な著者: Zubovych, Iryna O., Straud, Sarah, Roth, Michael G.
フォーマット: Artigo
言語:Inglês
出版事項: The American Society for Cell Biology 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836976/
https://ncbi.nlm.nih.gov/pubmed/20089839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-08-0673
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