Protein Phosphatase 2A Reactivates FOXO3a through a Dynamic Interplay with 14-3-3 and AKT

Forkhead box transcription factor FOXO3a, a key regulator of cell survival, is regulated by reversible phosphorylation and subcellular localization. Although the kinases regulating FOXO3a activity have been characterized, the role of protein phosphatases (PP) in the control of FOXO3a subcellular loc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Singh, Amrik, Ye, Min, Bucur, Octavian, Zhu, Shudong, Tanya Santos, Maria, Rabinovitz, Isaac, Wei, Wenyi, Gao, Daming, Hahn, William C., Khosravi-Far, Roya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Cell Biology 2010
Pynciau:
Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836964/
https://ncbi.nlm.nih.gov/pubmed/20110348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0795
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