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Abacavir and Metabolite Pharmacokinetics in HIV-1–Infected Children and Adolescents

OBJECTIVES: Abacavir (ABC) oral clearance, adjusted for body size, is approximately 2 times higher for children than adults with a corresponding difference in dose regimens. However, there are limited data available in the adolescent population. The pharmacokinetics (PKs) of ABC and primary metaboli...

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Autori principali: Cross, Shane J., Rodman, John H., Lindsey, Jane C., Robbins, Brian L., Rose, Charles H., Yuen, Geoffrey J., D'Angelo, Lawrence J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836884/
https://ncbi.nlm.nih.gov/pubmed/19282779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31819a2257
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