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Abacavir and Metabolite Pharmacokinetics in HIV-1–Infected Children and Adolescents
OBJECTIVES: Abacavir (ABC) oral clearance, adjusted for body size, is approximately 2 times higher for children than adults with a corresponding difference in dose regimens. However, there are limited data available in the adolescent population. The pharmacokinetics (PKs) of ABC and primary metaboli...
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Autori principali: | , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2009
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836884/ https://ncbi.nlm.nih.gov/pubmed/19282779 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31819a2257 |
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