Proteomic Identification of Binding Partners for the Brain Metabolite Lanthionine Ketimine (LK) and Documentation of LK Effects on Microglia and Motoneuron Cell Cultures

Lanthionine ketimine (LK) represents a poorly understood class of thioethers present in mammalian CNS. Previous work has indicated high-affinity interaction of LK with synaptosomal membrane protein(s), but neither LK binding partners nor specific bioactivities have been reported. In this study, LK w...

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Main Authors: Hensley, Kenneth, Christov, Alexandar, Kamat, Shekhar, Zhang, X. Cai, Jackson, Kenneth W., Snow, Stephen, Post, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836831/
https://ncbi.nlm.nih.gov/pubmed/20181595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5247-09.2010
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