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Signaling From Lysosomes Enhances Mitochondria-Mediated Photodynamic Therapy In Cancer Cells

In photodynamic therapy (PDT), visible light activates a photosensitizing drug added to a tissue, resulting in singlet oxygen formation and cell death. Assessed by confocal microscopy, the photosensitizer phthalocyanine 4 (Pc 4) localizes primarily to mitochondrial membranes in cancer cells, resulti...

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Detalhes bibliográficos
Main Authors: Quiogue, Geraldine, Saggu, Shalini, Hung, Hsin-I, Kenney, Malcolm E., Oleinick, Nancy L., Lemasters, John J., Nieminen, Anna-Liisa
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836728/
https://ncbi.nlm.nih.gov/pubmed/20228965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/12.823752
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