Spatiotemporal controlled delivery of nanoparticles to injured vasculature

There are a number of challenges associated with designing nanoparticles for medical applications. We define two challenges here: (i) conventional targeting against up-regulated cell surface antigens is limited by heterogeneity in expression, and (ii) previous studies suggest that the optimal size o...

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Bibliografiska uppgifter
Huvudupphovsmän: Chan, Juliana M., Zhang, Liangfang, Tong, Rong, Ghosh, Debuyati, Gao, Weiwei, Liao, Grace, Yuet, Kai P., Gray, David, Rhee, June-Wha, Cheng, Jianjun, Golomb, Gershon, Libby, Peter, Langer, Robert, Farokhzad, Omid C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836709/
https://ncbi.nlm.nih.gov/pubmed/20133865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914585107
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