Inherited genetic variant predisposes to aggressive but not indolent prostate cancer

Autopsy studies suggest that most aging men will develop lesions that, if detected clinically, would be diagnosed as prostate cancer (PCa). Most of these cancers are indolent and remain localized; however, a subset of PCa is aggressive and accounts for more than 27,000 deaths in the United States an...

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Hauptverfasser: Xu, Jianfeng, Zheng, Siqun Lilly, Isaacs, Sarah D., Wiley, Kathleen E., Wiklund, Fredrik, Sun, Jielin, Kader, A. Karim, Li, Ge, Purcell, Lina D., Kim, Seong-Tae, Hsu, Fang-Chi, Stattin, Pär, Hugosson, Jonas, Adolfsson, Jan, Walsh, Patrick C., Trent, Jeffrey M., Duggan, David, Carpten, John, Grönberg, Henrik, Isaacs, William B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836698/
https://ncbi.nlm.nih.gov/pubmed/20080650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914061107
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