Inherited genetic variant predisposes to aggressive but not indolent prostate cancer

Autopsy studies suggest that most aging men will develop lesions that, if detected clinically, would be diagnosed as prostate cancer (PCa). Most of these cancers are indolent and remain localized; however, a subset of PCa is aggressive and accounts for more than 27,000 deaths in the United States an...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Xu, Jianfeng, Zheng, Siqun Lilly, Isaacs, Sarah D., Wiley, Kathleen E., Wiklund, Fredrik, Sun, Jielin, Kader, A. Karim, Li, Ge, Purcell, Lina D., Kim, Seong-Tae, Hsu, Fang-Chi, Stattin, Pär, Hugosson, Jonas, Adolfsson, Jan, Walsh, Patrick C., Trent, Jeffrey M., Duggan, David, Carpten, John, Grönberg, Henrik, Isaacs, William B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2010
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836698/
https://ncbi.nlm.nih.gov/pubmed/20080650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914061107
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