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Methionine oxidation induces amyloid fibril formation by full-length apolipoprotein A-I

Apolipoprotein A-I (apoA-I) is the major protein component of HDL, where it plays an important role in cholesterol transport. The deposition of apoA-I derived amyloid is associated with various hereditary systemic amyloidoses and atherosclerosis; however, very little is known about the mechanism of...

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Главные авторы: Wong, Yuan Qi, Binger, Katrina J., Howlett, Geoffrey J., Griffin, Michael D. W.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836622/
https://ncbi.nlm.nih.gov/pubmed/20133843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910136107
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