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Toxin–antitoxin based transgene expression in mammalian cells
Long-term, recombinant gene expression in mammalian cells depends on the nature of the transgene integration site and its inherent properties to modulate transcription (epigenetic effects). Here we describe a method by which high transgene expression is achieved and stabilized in extensively prolife...
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Main Authors: | , , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
Oxford University Press
2010
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836568/ https://ncbi.nlm.nih.gov/pubmed/20007149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1140 |
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