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Toxin–antitoxin based transgene expression in mammalian cells

Long-term, recombinant gene expression in mammalian cells depends on the nature of the transgene integration site and its inherent properties to modulate transcription (epigenetic effects). Here we describe a method by which high transgene expression is achieved and stabilized in extensively prolife...

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Bibliographic Details
Main Authors: Nehlsen, K., Herrmann, S., Zauers, J., Hauser, H., Wirth, D.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836568/
https://ncbi.nlm.nih.gov/pubmed/20007149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1140
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