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Telomerase activity: A biomarker of cell proliferation, not malignant transformation

Telomerase activity is readily detected in most cancer biopsies, but not in premalignant lesions or in normal tissue samples with a few exceptions that include germ cells and hemopoietic stem cells. Telomerase activity may, therefore, be a useful biomarker for diagnosis of malignancies and a target...

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Bibliografische gegevens
Hoofdauteurs: Belair, Cassandra D., Yeager, Thomas R., Lopez, Patricia M., Reznikoff, Catherine A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1997
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC28365/
https://ncbi.nlm.nih.gov/pubmed/9391085
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