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Telomerase activity in pleural malignant mesotheliomas

New treatments are needed for malignant pleural mesothelioma (MPM), which currently has a poor prognosis. Cellular immortalisation, one of the hallmarks of cancer, depends on the activity of a telomere length maintenance mechanism (TMM) – either telomerase or alternative lengthening of telomeres (AL...

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Autors principals: Au, Amy Y.M., Hackl, Torben, Yeager, Thomas R., Cohen, Scott B., Pass, Harvey I., Harris, Curtis C., Reddel, Roger R.
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135747/
https://ncbi.nlm.nih.gov/pubmed/21277646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lungcan.2010.12.023
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