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Inhibition of brain [(3)H]cimetidine binding by improgan-like antinociceptive drugs
[(3)H]Cimetidine, a radiolabeled histamine H(2) receptor antagonist, binds with high affinity to an unknown hemoprotein in the brain which is not the histamine H(2) receptor. Improgan, a close chemical congener of cimetidine, is a highly effective pain-relieving drug following CNS administration, ye...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836490/ https://ncbi.nlm.nih.gov/pubmed/20138862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2010.01.026 |
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