Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype

BACKGROUND: Autophagy, an intracellular response to stress, is characterized by double membrane cytosolic vesicles called autophagosomes. Prolonged autophagy is known to result in autophagic (Type II) cell death. This study examined the potential role of an autophagic response in cultured cerebellar...

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Библиографические подробности
Главные авторы: Sadasivan, Shankar, Zhang, Zhiqun, Larner, Stephen F, Liu, Ming C, Zheng, Wenrong, Kobeissy, Firas H, Hayes, Ronald L, Wang, Kevin KW
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2010
Предметы:
Research article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836363/
https://ncbi.nlm.nih.gov/pubmed/20167092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-11-21
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