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Measuring intracellular pH in the heart using hyperpolarized carbon dioxide and bicarbonate: a (13)C and (31)P magnetic resonance spectroscopy study

AIMS: Technological limitations have restricted in vivo assessment of intracellular pH (pH(i)) in the myocardium. The aim of this study was to evaluate the potential of hyperpolarized [1-(13)C]pyruvate, coupled with (13)C magnetic resonance spectroscopy (MRS), to measure pH(i) in the healthy and dis...

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Detalhes bibliográficos
Main Authors: Schroeder, Marie A., Swietach, Pawel, Atherton, Helen J., Gallagher, Ferdia A., Lee, Phillip, Radda, George K., Clarke, Kieran, Tyler, Damian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836261/
https://ncbi.nlm.nih.gov/pubmed/20008827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp396
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