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Zinc-Binding Groups Modulate Selective Inhibition of MMPs

The need for selective matrix metalloproteinase (MMP) inhibition is of interest because of the range of pathologies mediated by different MMP isoforms. The development of more selective MMP inhibitors (MMPi) may help to overcome some of the undesired side effects that have hindered the clinical succ...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Agrawal, Arpita, Romero-Perez, Diego, Jacobsen, Jennifer A., Villarreal, Francisco J., Cohen, Seth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836234/
https://ncbi.nlm.nih.gov/pubmed/18181119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.200700290
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