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GSK-3 Represses Growth Factor-inducible Genes by Inhibiting NF-κB in Quiescent Cells

GSK-3 is active in the absence of growth factor stimulation and generally acts to induce apoptosis or inhibit cell proliferation. We previously identified a subset of growth factor-inducible genes that can also be induced in quiescent T98G cells solely by inhibition of GSK-3 in the absence of growth...

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Autori principali: Graham, Julie R., Tullai, John W., Cooper, Geoffrey M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836053/
https://ncbi.nlm.nih.gov/pubmed/20018891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.053785
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