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A GSK-3-mediated transcriptional network maintains repression of immediate early genes in quiescent cells

Glycogen synthase kinase-3 (GSK-3) plays a central role in cell survival and proliferation, in part by the regulation of transcription. Unlike most protein kinases, GSK-3 is active in quiescent cells in the absence of growth factor signaling. In a recent series of studies, we employed a systems-leve...

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Auteurs principaux: Tullai, John W, Graham, Julie R, Cooper, Geoffrey M
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218618/
https://ncbi.nlm.nih.gov/pubmed/21900749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.18.17321
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