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MicroRNAs Regulate Human Hepatocyte Nuclear Factor 4α, Modulating the Expression of Metabolic Enzymes and Cell Cycle

Hepatocyte nuclear factor (HNF) 4α is a key transcription factor regulating endo/xenobiotic-metabolizing enzymes and transporters. We investigated whether microRNAs are involved in the regulation of human HNF4α. Potential recognition elements for miR-24 (MRE24) were identified in the coding region a...

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Detalhes bibliográficos
Main Authors: Takagi, Shingo, Nakajima, Miki, Kida, Katsuhiko, Yamaura, Yu, Fukami, Tatsuki, Yokoi, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836046/
https://ncbi.nlm.nih.gov/pubmed/20018894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.085431
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