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Aptamer-targeted cell-specific RNA interference

This potent ability of small interfering (si)RNAs to inhibit the expression of complementary RNA transcripts is being exploited as a new class of therapeutics for a variety of diseases. However, the efficient and safe delivery of siRNAs into specific cell populations is still the principal challenge...

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Detalhes bibliográficos
Main Authors: Zhou, Jiehua, Rossi, John J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835998/
https://ncbi.nlm.nih.gov/pubmed/20226078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-907X-1-4
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