cAMP activates the generation of reactive oxygen species and inhibits the secretion of IL-6 in peripheral blood mononuclear cells from type 2 diabetic patients

Peripheral blood mononuclear cells (PBMNC) from patients with type 2 diabetes (DM2) have generated higher levels of reactive oxygen species (ROS) that were higher than those in cells from healthy individuals. In the presence of a cAMP-elevating agent, ROS production was significantly activated in PB...

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Bibliographic Details
Main Authors: Isoni, Camila Armond, Borges, Érica Abreu, Veloso, Clara Araújo, Mattos, Rafael Teixeira, Chaves, Miriam Martins, Nogueira-Machado, José Augusto
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2009
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835920/
https://ncbi.nlm.nih.gov/pubmed/20716919
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