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Spatio-Temporal Modeling of Nanoparticle Delivery to Multicellular Tumor Spheroids
The inefficiency of nanoparticle penetration in tissues limits the therapeutic efficacy of such formulations for cancer applications. Recent work has indicated that modulation of tissue architecture with enzymes such as collagenase significantly increases macromolecule delivery. In this study we dev...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835857/ https://ncbi.nlm.nih.gov/pubmed/18500767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.21910 |
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