Yüklüyor......

Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde

Instability of repetitive sequences is a hallmark of human cancer, and its enhancement has been linked to oxidative stress. Malondialdehyde is an endogenous product of oxidative stress that reacts with guanine to form the exocyclic adduct, pyrimido[1,2- α]purin-10(3H)-one (M(1)G). We used site-speci...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: VanderVeen, Laurie A., Hashim, Muhammed F., Shyr, Yu, Marnett, Lawrence J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283577/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14603032/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2332176100
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!