Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology

Carbonic anhydrase IX (CAIX, gene G250/MN-encoded transmembrane protein) is highly expressed in various human epithelial tumors such as renal clear cell carcinoma (RCC), but absent from the corresponding normal tissues. Besides the CA signal transduction activity, CAIX may serve as a biomarker in ea...

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Detalhes bibliográficos
Main Authors: Xu, Chen, Lo, Agnes, Yammanuru, Anuradha, Tallarico, Aimee St. Clair, Brady, Kristen, Murakami, Akikazu, Barteneva, Natasha, Zhu, Quan, Marasco, Wayne A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835754/
https://ncbi.nlm.nih.gov/pubmed/20224781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009625
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