Unique Biological Properties of Catalytic Domain Directed Human Anti-CAIX Antibodies Discovered through Phage-Display Technology

Carbonic anhydrase IX (CAIX, gene G250/MN-encoded transmembrane protein) is highly expressed in various human epithelial tumors such as renal clear cell carcinoma (RCC), but absent from the corresponding normal tissues. Besides the CA signal transduction activity, CAIX may serve as a biomarker in ea...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xu, Chen, Lo, Agnes, Yammanuru, Anuradha, Tallarico, Aimee St. Clair, Brady, Kristen, Murakami, Akikazu, Barteneva, Natasha, Zhu, Quan, Marasco, Wayne A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835754/
https://ncbi.nlm.nih.gov/pubmed/20224781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009625
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