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Expanding the utility of β-galactosidase complementation: piece by piece

The ability to image and quantify multiple biomarkers in disease necessitates the development of split reporter fragment platforms. We have divided the β-galactosidase enzyme into unique, independent polypeptides that are able to re-assemble and complement enzymatic activity in bacteria and in mamma...

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Autors principals: Broome, Ann-Marie, Bhavsar, Nihir, Ramamurthy, Gopal, Newton, Gail, Basilion, James P.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835542/
https://ncbi.nlm.nih.gov/pubmed/19899815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp900188e
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