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Seventy-Five Percent Nephrectomy and the Disposition of Inorganic Mercury in 2,3-Dimercaptopropanesulfonic Acid-Treated Rats Lacking Functional Multidrug-Resistance Protein 2

In the present study, we evaluated the disposition of inorganic mercury (Hg(2+)) in sham-operated and 75% nephrectomized (NPX) Wistar and transport-deficient (TR(−)) rats treated with saline or the chelating agent meso-2,3-dimercaptosuccinic acid (DMSA). Based on previous studies, DMSA and TR(−) rat...

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Detalhes bibliográficos
Main Authors: Zalups, Rudolfs K., Bridges, Christy C.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835429/
https://ncbi.nlm.nih.gov/pubmed/20032202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.163774
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