Lentiviral Vectors Transduce Proliferating Dendritic Cell Precursors Leading to Persistent Antigen Presentation and Immunization

Lentiviral vectors (LVs) are tools for in vivo gene delivery, to correct genetic defects or to deliver antigens for vaccination. It was reported that systemic injection of LVs in mice transduced cells in liver and spleen. Here we describe the reasons for, and consequences of, persistent gene express...

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Bibliographische Detailangaben
Hauptverfasser: Arce, Frederick, Rowe, Helen M, Chain, Benjamin, Lopes, Luciene, Collins, Mary K
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835272/
https://ncbi.nlm.nih.gov/pubmed/19584812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.149
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