Drug Delivery–mediated Control of RNA Immunostimulation

RNA interference (RNAi) has generated significant interest as a strategy to suppress viral infection, but in some cases antiviral activity of unmodified short-interfering RNA (siRNA) has been attributed to activation of innate immune responses. We hypothesized that immunostimulation by unmodified si...

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Hlavní autoři: Nguyen, David N., Chen, Steve C-Y, Lu, James, Goldberg, Michael, Kim, Phillip, Sprague, Andrew, Novobrantseva, Tatiana, Sherman, Jennifer, Shulga-Morskaya, Svetlana, de Fougerolles, Antonin, Chen, Jianzhu, Langer, Robert, Anderson, Daniel G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835254/
https://ncbi.nlm.nih.gov/pubmed/19584813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.147
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