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Sonic Hedgehog Expands Diaphyseal Trabecular Bone Altering Bone Marrow Niche and Lymphocyte Compartment

Bone marrow contains distinct microenvironments that regulate hematopoietic stem cells (HSCs). The endosteal HSC niche includes osteoblasts, mineral, and extracellular matrix proteins that interact through various molecular signals to control HSCs. Sonic hedgehog (Shh) is a morphogen involved in the...

詳細記述

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書誌詳細
主要な著者: Kiuru, Maija, Hidaka, Chisa, Hubner, Ralf-Harto, Solomon, Jason, Krause, Anja, Leopold, Philip L, Crystal, Ronald G
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835226/
https://ncbi.nlm.nih.gov/pubmed/19436267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.102
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