Sonic Hedgehog Expands Diaphyseal Trabecular Bone Altering Bone Marrow Niche and Lymphocyte Compartment

Bone marrow contains distinct microenvironments that regulate hematopoietic stem cells (HSCs). The endosteal HSC niche includes osteoblasts, mineral, and extracellular matrix proteins that interact through various molecular signals to control HSCs. Sonic hedgehog (Shh) is a morphogen involved in the...

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Detalhes bibliográficos
Main Authors: Kiuru, Maija, Hidaka, Chisa, Hubner, Ralf-Harto, Solomon, Jason, Krause, Anja, Leopold, Philip L, Crystal, Ronald G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835226/
https://ncbi.nlm.nih.gov/pubmed/19436267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.102
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