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Intravascularly Administered RGD-Displaying Measles Viruses Bind to and Infect Neovessel Endothelial Cells In Vivo

Systemically administered vectors must cross the endothelial lining of tumor blood vessels to access cancer cells. Vectors that interact with markers on the lumenal surface of these endothelial cells might have enhanced tumor localization. Here, we generated oncolytic measles viruses (MVs) displayin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ong, Hooi Tin, Trejo, Theodore R, Pham, Linh D, Oberg, Ann L, Russell, Stephen J, Peng, Kah-Whye
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835192/
https://ncbi.nlm.nih.gov/pubmed/19277014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.39
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