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Engineering Clustered Ligand Binding Into Nonviral Vectors: α(v)β(3) Targeting as an Example

The development of techniques to efficiently deliver genes using nonviral approaches can broaden the application of gene delivery in medical applications without the safety concerns associated with viral vectors. Here, we designed a clustered integrin-binding platform to enhance the efficiency and t...

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Autores principales: Ng, Quinn KT, Sutton, Marie K, Soonsawad, Pan, Xing, Li, Cheng, Holland, Segura, Tatiana
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835129/
https://ncbi.nlm.nih.gov/pubmed/19240693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.11
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