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Replication protein A-mediated recruitment and activation of Rad17 complexes

The human Rad17–Rfc2-5 and Rad9–Rad1–Hus1 complexes play crucial roles in the activation of the ATR-mediated DNA damage and DNA replication stress response pathways. In response to DNA damage, Rad9 is recruited to chromatin in a Rad17-dependent manner in human cells. However, the DNA structures reco...

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Detalhes bibliográficos
Main Authors: Zou, Lee, Liu, Dou, Elledge, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC283506/
https://ncbi.nlm.nih.gov/pubmed/14605214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2336100100
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