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Vesicular Stomatitis Virus as a Novel Cancer Vaccine Vector to Prime Antitumor Immunity Amenable to Rapid Boosting With Adenovirus

Vesicular stomatitis virus (VSV) has proven to be an effective vaccine vector for immunization against viral infection, but its potential to induce an immune response to a self-tumor antigen has not been investigated. We constructed a recombinant VSV expressing human dopachrome tautomerase (hDCT) an...

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Détails bibliographiques
Auteurs principaux: Bridle, Byram W, Boudreau, Jeanette E, Lichty, Brian D, Brunellière, Jérôme, Stephenson, Kyle, Koshy, Sandeep, Bramson, Jonathan L, Wan, Yonghong
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835010/
https://ncbi.nlm.nih.gov/pubmed/19603003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.154
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