Transduction Efficiency and Immune Response Associated With the Administration of AAV8 Vector Into Dog Skeletal Muscle

Recombinant adeno-associated virus (rAAV)-mediated gene transfer is an attractive approach to the treatment of Duchenne muscular dystrophy (DMD). We investigated the muscle transduction profiles and immune responses associated with the administration of rAAV2 and rAAV8 in normal and canine X-linked...

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Main Authors: Ohshima, Sachiko, Shin, Jin-Hong, Yuasa, Katsutoshi, Nishiyama, Akiyo, Kira, Junichi, Okada, Takashi, Takeda, Shin'ichi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2008
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834993/
https://ncbi.nlm.nih.gov/pubmed/18941441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.225
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