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Gene-mediated Restoration of Normal Myofiber Elasticity in Dystrophic Muscles

Dystrophin mediates a physical link between the cytoskeleton of muscle fibers and the extracellular matrix, and its absence leads to muscle degeneration and dystrophy. In this article, we show that the lack of dystrophin affects the elasticity of individual fibers within muscle tissue explants, as p...

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Detalhes bibliográficos
Main Authors: Puttini, Stefania, Lekka, Małgorzata, Dorchies, Olivier M, Saugy, Damien, Incitti, Tania, Ruegg, Urs T, Bozzoni, Irene, Kulik, Andrzej J, Mermod, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834969/
https://ncbi.nlm.nih.gov/pubmed/19002166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.239
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