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Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes

Duchenne muscular dystrophy (DMD) is a lethal disease caused by the lack of the cytoskeletal protein dystrophin. Altered calcium homoeostasis and increased calcium concentrations in dystrophic fibres may be responsible for the degeneration of muscle occurring in DMD. In the present study, we used su...

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Detalles Bibliográficos
Main Authors: Basset, Olivier, Boittin, François-Xavier, Cognard, Christian, Constantin, Bruno, Ruegg, Urs T.
Formato: Artigo
Idioma:Inglês
Publicado: Portland Press Ltd. 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422769/
https://ncbi.nlm.nih.gov/pubmed/16393138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051265
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