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Bcl-2 overexpression prevents calcium overload and subsequent apoptosis in dystrophic myotubes

Duchenne muscular dystrophy (DMD) is a lethal disease caused by the lack of the cytoskeletal protein dystrophin. Altered calcium homoeostasis and increased calcium concentrations in dystrophic fibres may be responsible for the degeneration of muscle occurring in DMD. In the present study, we used su...

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Autori principali: Basset, Olivier, Boittin, François-Xavier, Cognard, Christian, Constantin, Bruno, Ruegg, Urs T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Portland Press Ltd. 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1422769/
https://ncbi.nlm.nih.gov/pubmed/16393138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051265
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