Suppression of the Intrinsic Apoptosis Pathway by Synaptic Activity

Synaptic activity promotes resistance to diverse apoptotic insults, the mechanism behind which is incompletely understood. We show here that a coordinated downregulation of core components of the intrinsic apoptosis pathway by neuronal activity forms a key part of the underlying mechanism. Activity-...

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Autori principali: Léveillé, Frédéric, Papadia, Sofia, Fricker, Michael, Bell, Karen F. S., Soriano, Francesc X., Martel, Marc-André, Puddifoot, Clare, Habel, Marlen, Wyllie, David J., Ikonomidou, Chrysanthy, Tolkovsky, Aviva M., Hardingham, Giles E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834927/
https://ncbi.nlm.nih.gov/pubmed/20164347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5115-09.2010
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